The immortelle or Helichrysum Italicum is a characteristic plant of the Mediterranean basin. The name Helichrysum comes from the Greek "helios", which means sun, and "chrysos", which means gold. Its common name of Immortelle comes from the fact that its flowers keep their yellow color even when they dry out. The floral water is extracted by hydrodistillation.

In-Vitro :
> 148% increase in the release of b-endorphins (relaxing molecules)
> Significant decreases in inflammation mediators in post-aggression (-50% for example for Interleukin 5, 5 other mediators were tested)
> Increase in the concentrations of enzymes that help fight against oxidative stress (catalase +77% and gluthation peroxidase +85%)
> Strengthening of the skin barrier via an increase in the synthesis of key proteins shaping the stratum corneum (such as cytokeratins, filaggrin...) and optimizing cell cohesion

In-Vivo :
> Immediate reduction of tingling sensations by 34% 1 minute after application, and by 79% after 5 minutes.
> Immediate soothing of 100% of volunteers in 5 minutes
> 17% reduction in insensible water loss (IWL) after 3 days of use
> 48% reduction in skin reactivity after 14 days of application

The Four O’Clock Flower, also known as “Wonder of Peru”, is a plant of subtropical American origin. Its roots and flowers have been used for centuries for their medicinal virtues on: headaches, wounds and stings…

In-Vitro:
> 25% decrease in TRPV1 after irritant stress, a molecule that increases the sensitivity of nerve cells
> 49% decrease in discomfort messengers (NGF)
> 164% increase in hyaluronic acid, the skin's water reservoir
> Strengthening of the skin barrier via an increase in the synthesis of key proteins (filaggrin +44%, occludin +107%...) shaping the stratum corneum and optimizing cell cohesion
> Reinforcement of the cutaneous barrier via a restoration of the key lipids of the intercellular cement (ceramides - +45% after 2 months of use).

In-Vivo :
> 30% reduction in sensations of discomfort after exposure to irritating agents in just 3 minutes. After regular use (2 months), discomfort sensations are perceived as moderate.
>Long-term improvement in skin sensitivity (21 days of treatment): -80% itching sensations, a decrease of 86% in tingling
> 54% reduction in redness perceived on the face after 21 days
> 45% decrease in insensible water loss after 2 months
> 11.5% increase in the thickness of the epidermis after 21 days
> 77% of the sample found their skin hydrated after 2 months
> 83% of the sample found their skin comfortable after 2 months

This soothing active ingredient comes from the Centella Asisatica plant, also called Tiger Grass and is known for its soothing, anti-inflammatory and healing properties.

In-Vitro:
> Significant decrease in the presence of pro-inflammatory agents (-42%)
> Regulation of the production of inflammation mediators (such as Interleukins 1 and 8 for example)
> Proven antioxidant action
> Strengthening of the skin barrier via an increase in the synthesis of key proteins shaping the stratum corneum (notably filaggrin)

In-Vivo :
> 101% increase in hydration after 56 days
> 65% decrease in itching sensation after 56 days